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Dupilumab ELISA Kit (DB732018)

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Overview
Catalog No.DB732018
Description
Dupilumab ELISA Kit (DB732018) — Quantitative sandwich ELISA for Dupilumab. Sample: Plasma, Serum. Range: 78.125 ng/mL - 5, 000 ng/mL.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Range78.125 ng/mL - 5, 000 ng/mL
Accession P24394
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 90-120%
Shipping 2-8 ℃
Stability and Storage When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃.
Specifications

Dupilumab

Alternate NamesCD124, REGN668, SAR231893, 1190264-60-8
Background

Interleukin-4 receptor subunit alpha (Dupilumab) is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238
Note For Research Use Only.
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References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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