

| Catalog No. | DB732018 |
|---|---|
| Description |
Dupilumab ELISA Kit (DB732018) — Quantitative sandwich ELISA for Dupilumab. Sample: Plasma, Serum. Range: 78.125 ng/mL - 5, 000 ng/mL.
Highlights
|
| Sample type | Plasma, Serum |
| Range | 78.125 ng/mL - 5, 000 ng/mL |
| Accession | P24394 |
| Applications | ELISA |
| Detection method | Colorimetric |
| Assay type | Quantitative |
| Recovery | 90-120% |
| Shipping | 2-8 ℃ |
| Stability and Storage | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃. |
| Specifications | Dupilumab |
| Alternate Names | CD124, REGN668, SAR231893, 1190264-60-8 |
| Background | Interleukin-4 receptor subunit alpha (Dupilumab) is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. 1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238 |
| Note | For Research Use Only. |




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