Bimagrumab ELISA Kit (DB949018)

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Overview

Catalog No.	DB949018
Description	_x005F_x000d_ _x005F_x000d_ _x005F_x000d_ _x005F_x000d_ _x005F_x000d_ _x005F_x000d_ Bimagrumab ELISA Kit (DB949018) — Quantitative sandwich ELISA for Bimagrumab. Sample: Plasma, Serum. Range: 125 - 4, 000 ng/mL. Sensitivity: 97.28 ng/mL. _x005F_x000d_ _x005F_x000d_ _x005F_x000d_ Highlights _x005F_x000d_ _x005F_x000d_ _x005F_x000d_ ●Sandwich Format — High specificity, reliable quantification. _x005F_x000d_ ●High Sensitivity — Optimized for low-abundance target detection. _x005F_x000d_ ●Ready-to-Use — Complete kit with pre-coated plates included. _x005F_x000d_ _x005F_x000d_ _x005F_x000d_
Sample type	Serum, plasma, and other biological fluid samples
Sensitivity	3.73 ng/mL
Range	31.25 – 1,000 ng/mL
Species reactivity	Human
Target	ACVR2A,ACVR2B
Accession	P27037,Q13705
Applications	ELISA
Detection method	Colorimetric
Assay type	Competitive
Recovery	80-120%
Shipping	2-8 ℃
Stability and Storage	When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20 ℃, the rest reagents should be store at 4℃.
Specifications	Bimagrumab _x005F_x000d_
Alternate Names	BYM338, 1356922-05-8
Background	Bimagrumab is a monoclonal anti-ActRIIA/IIB antibody that targets ActRIIA and ActRIIB simultaneously. Native ActRIIA and ActRIIB are both mediators of signaling from several TGFβ superfamily members such as activins, myostatin, and GDF11. Hence, pan-blockade by Bimagrumab achieves greater effect than a monoclonal antibody against either receptor alone, i.e. monotherapy with anti-ActRIIA antibody or anti-ActRIIB antibody. Bimagrumab has been explored as a therapy for sporadic inclusion body myositis, primary sarcopenia, and muscle wasting associated with chronic obstructive pulmonary disease. _x005F_x000d_
Note	For Research Use Only.

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Standard Curve

Standard Curve of Bimagrumab ELISA Kit

References

Datasheet

Bimagrumab ELISA Kit.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Bimagrumab ELISA Kit (DB949018)

Overview

Images

References

Datasheet

SDS