Anti-Eculizumab Neutralizing Antibody ELISA kit (AF687028)

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Overview

Catalog No.	AF687028
Description	Anti-Eculizumab Neutralizing Antibody ELISA kit (AF687028) — Quantitative sandwich ELISA for Anti-Eculizumab Neutralizing Antibody. Sample: Plasma, Serum. Range: 15.625-1, 000 ng/ml. Highlights ●Sandwich Format — High specificity, reliable quantification. ●Ready-to-Use — Complete kit with pre-coated plates included.
Sample type	Plasma, Serum
Range	15.625-1, 000 ng/ml
Accession	P01031
Applications	ELISA
Detection method	Colorimetric
Assay type	Quantitative
Recovery	80-120%
Shipping	2-8 ℃
Stability and Storage	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications	Eculizumab
Alternate Names	5G1.1, h5G1.1HuG2/G4, 219685-50-4
Background	Complement C5 (Eculizumab) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019 4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279 5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882
Note	For Research Use Only.