

| Catalog No. | AY286518 |
|---|---|
| Description |
Anti-Pertuzumab Neutralizing Antibody ELISA kit (AY286518) — Quantitative sandwich ELISA for Anti-Pertuzumab Neutralizing Antibody. Sample: Plasma, Serum. Range: 15.625-1, 000 ng/ml.
Highlights
|
| Sample type | Plasma, Serum |
| Range | 15.625-1, 000 ng/ml |
| Accession | P04626 |
| Applications | ELISA |
| Detection method | Colorimetric |
| Assay type | Quantitative |
| Recovery | 80-120% |
| Shipping | 2-8 ℃ |
| Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| Specifications | Pertuzumab |
| Alternate Names | OMNITARG, rhuMAB 2C4, 380610-27-5 |
| Background | Receptor tyrosine-protein kinase erbB-2 (Pertuzumab) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. |
| Note | For Research Use Only. |
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