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Teprotumumab ELISA Kit (DY353058)

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Overview
Catalog No.DY353058
Description
Teprotumumab ELISA Kit (DY353058) — Quantitative sandwich ELISA for Teprotumumab. Sample: Plasma, Serum. Range: 62.5 ng/mL - 4, 000 ng/mL.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Range62.5 ng/mL - 4, 000 ng/mL
Accession P08069
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 80-120%
Shipping 2-8 ℃
Stability and Storage When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃.
Specifications

Teprotumumab

Alternate NamesRO4858696-000, 1036734-93-6
Background

Insulin-like growth factor 1 receptor (Teprotumumab) is a ~154 kDa protein. Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins.

Note For Research Use Only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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