

| Catalog No. | DY353058 |
|---|---|
| Description |
Teprotumumab ELISA Kit (DY353058) — Quantitative sandwich ELISA for Teprotumumab. Sample: Plasma, Serum. Range: 62.5 ng/mL - 4, 000 ng/mL.
Highlights
|
| Sample type | Plasma, Serum |
| Range | 62.5 ng/mL - 4, 000 ng/mL |
| Accession | P08069 |
| Applications | ELISA |
| Detection method | Colorimetric |
| Assay type | Quantitative |
| Recovery | 80-120% |
| Shipping | 2-8 ℃ |
| Stability and Storage | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃. |
| Specifications | Teprotumumab |
| Alternate Names | RO4858696-000, 1036734-93-6 |
| Background | Insulin-like growth factor 1 receptor (Teprotumumab) is a ~154 kDa protein. Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. |
| Note | For Research Use Only. |
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