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InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20) (VK518010)

InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20)
InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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  • Datasheet

Overview
Catalog No.VK518010
Description
InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20) [MJ20] (VK518010) is a human monoclonal antibody detecting Nucleoprotein in ELISA, IF, Neutralization, SPR.
Highlights
  • Multi-Application — Validated across multiple applications.
Species reactivityReston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus), Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus), Bundibugyo ebolavirus, Tai Forest ebolavirus
ApplicationsELISA, IF, Neutralization, SPR
Host speciesHuman
IsotypeIgG
Clone IDMJ20
Clonality Monoclonal
Target Nucleoprotein, Ebola NP, eNP, Nucleocapsid protein, Protein N, NP
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q8JPY1, P18272, B8XCM7, B8XCN6
RRID InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20) (abinScience Cat# VK518010, RRID:AB_3727235)
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Nucleoprotein (NP) is a ~83 kDa protein. Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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