

| Catalog No. | VK518010 |
|---|---|
| Description |
InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20) [MJ20] (VK518010) is a human monoclonal antibody detecting Nucleoprotein in ELISA, IF, Neutralization, SPR.
Highlights
|
| Species reactivity | Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus), Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus), Bundibugyo ebolavirus, Tai Forest ebolavirus |
| Applications | ELISA, IF, Neutralization, SPR |
| Host species | Human |
| Isotype | IgG |
| Clone ID | MJ20 |
| Clonality | Monoclonal |
| Target | Nucleoprotein, Ebola NP, eNP, Nucleocapsid protein, Protein N, NP |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q8JPY1, P18272, B8XCM7, B8XCN6 |
| RRID | InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20) (abinScience Cat# VK518010, RRID:AB_3727235) |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Nucleoprotein (NP) is a ~83 kDa protein. Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-REBOV/SEBOV/TAFV/ZEBOV NP/Nucleoprotein Antibody (MJ20)
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