

| Catalog No. | HA985023 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA2514 | ||||
| Clonality | Monoclonal | ||||
| Target | AQP-3, AQP3, Aquaglyceroporin-3, Aquaporin-3 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q92482 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Aquaporin-3 (AQP3) is a ~31 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance. 1. Roudier, N. et al. (2002) The Journal of biological chemistry 277, 45854-9. PMID: 12239222 2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639 3. Miller, EW. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 15681-6. PMID: 20724658 | ||||
| Note | For research use only | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human AQP3 Antibody (SAA2514)
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