Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11) (MY282107)

Name: Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11)
Brand: abinScience
SKU: MY282107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	MY282107
Species reactivity	Mouse
Applications	ELISA, FCM, Neutralization
Host species	Mouse
Isotype	IgG2a
Clone ID	2G11
Clonality	Monoclonal
Target	IGF2R, M6P/IGF2 receptor, 300 kDa mannose 6-phosphate receptor, IGF-II receptor, M6PR, CI-MPR, CD222, Insulin-like growth factor 2 receptor, MPR 300, M6P/IGF2R, MPRI, CI Man-6-P receptor, Insulin-like growth factor II receptor, Cation-independent mannose-6-phosphate receptor
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q07113
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Cation-independent mannose-6-phosphate receptor (CD222/IGF2R) is a ~273 kDa protein. Mediates the transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation by binding DPP4.
Note	For research use only.

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Datasheet

Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11).pdf

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Anti-Mouse CD222/IGF2R Recombinant Antibody (2G11) (MY282107)

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