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Research Grade Vilobelimab (HF687086)

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  • 100ug
  • 1mg
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Overview
Catalog No.HF687086
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesChimeric
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetCPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP01031
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesCaCP-29,IFX-1,CAS:2250440-41-4
BackgroundVilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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