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|---|---|
| Species reactivity | Human | 
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | 
| Host species | Humanized | 
| Isotype | IgG4-kappa | 
| Expression system | Mammalian Cells | 
| Clonality | Monoclonal | 
| Target | MAPTL, Paired helical filament-tau, MTBT1, Microtubule-associated protein tau, TAU, Neurofibrillary tangle protein, MAPT, PHF-tau | 
| Endotoxin level | Please contact the lab for this information. | 
| Purity | >95% purity as determined by SDS-PAGE. | 
| Purification | Protein A/G purified from cell culture supernatant. | 
| Accession | P10636 | 
| Form | Liquid | 
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. | 
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | 
| Alternate Names | RO-7105705, 2159141-27-0 | 
| Background | Posdinemab is a humanized IgG1κ antibody, targeting to microtubule-associated protein tau (MAPT). | 
| Note | For research use only. Not suitable for clinical or therapeutic use. | 

SDS-PAGE for Research Grade Semorinemab.

SEC-HPLC detection for Research Grade Semorinemab.

Detects Human MAPT/Tau/PHF-tau in indirect ELISAs.




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