| Catalog No. | YP464016 |
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| Species reactivity | General |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Chimeric |
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| Isotype | IgG1-kappa |
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| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Ganglioside GD3 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
PubChem CID: 20057323 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | KM871, KW-2871, CAS: 292819-64-8 |
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| Background | Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma.
• GD3 ganglioside and apoptosis., PMID:12531552
• Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474
• Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197
• A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669
• Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994
• Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773
• Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804
• Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478
• Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859
• Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428
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| Note |
For research use only. Not suitable for clinical or therapeutic use. |
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