Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (YP862016)

Name: Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO)
Brand: abinScience
SKU: YP862016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	YP862016
Description	Bavituximab (YP862016) is a research-grade recombinant antibody targeting Phosphatidylserine. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	General
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Chimeric
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Phosphatidylserine
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	1446756-47-3
RRID	Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (abinScience Cat# YP862016, RRID:AB_3751823)
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	Tarvacinch3 G4, CAS: 648904-28-3
Background	Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer. • Phosphatidylserine and the human brain., PMID:25933483 • The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774 • Phosphatidylserine transport in cell life and death., PMID:37413778 • Phosphatidylserine., PMID:10541030 • Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225 • Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192 • Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347 • Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133 • Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986 • Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Bavituximab.
SDS-PAGE

SDS-PAGE for Research Grade Bavituximab

References

Phosphatidylserine-everted erythrocyte membrane vesicles enhance efferocytosis and remodeling of vascular grafts

Datasheet

Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO).pdf

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Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (YP862016)

Overview

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References

Datasheet

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