| Catalog No. | YP862016 |
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| Species reactivity | General |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Chimeric |
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| Isotype | IgG1-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | Phosphatidylserine |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | 1446756-47-3 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | Tarvacinch3G4, 648904-28-3 |
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| Background | Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer.
• Phosphatidylserine and the human brain., PMID:25933483
• The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774
• Phosphatidylserine transport in cell life and death., PMID:37413778
• Phosphatidylserine., PMID:10541030
• Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225
• Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192
• Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347
• Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133
• Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986
• Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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