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Research Grade Exbivirumab (VK539026)

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Research Grade Exbivirumab

Research Grade Exbivirumab

Research Grade Exbivirumab

Research Grade Exbivirumab

Research Grade Exbivirumab

Research Grade Exbivirumab

Price(USD): $

Spec:

100ug
1mg

Number:

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Overview
Images
References
Datasheet

Overview

Catalog No.	VK539026
Description	Exbivirumab (VK539026) is a research-grade recombinant antibody targeting Large envelope protein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Hepatitis B virus genotype A (HBV-A)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, lambda
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P03142
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	19.79.5, HepeX-B(combinationofexbivirumabandlibivirumab), 569658-80-6
Background	Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Exbivirumab.
Bioactivity

Detects S/L-HBsAg/L glycoprotein in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Exbivirumab

References

Datasheet

Research Grade Exbivirumab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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V₁ (Stock Vol.)

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Working Solution

C₂ (Working Conc.)

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Research Grade Exbivirumab