



| Catalog No. | VK515046 | ||||
|---|---|---|---|---|---|
| Description |
Gedivumab (VK515046) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Species reactivity | Influenza A virus (H1, H2, H3, H5, H7 subtype) | ||||
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| Host species | Human | ||||
| Isotype | IgG1, kappa | ||||
| Expression system | Mammalian cells | ||||
| Clonality | Monoclonal | ||||
| Target | HA/Hemagglutinin | ||||
| Endotoxin level | < 10 EU/mg | ||||
| Purity | >95% purity as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | C6KNH7 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Alternate Names | MHAA4549A, RO6876802, RG7745, 1807954-17-1 | ||||
| Background | Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Gedivumab.

SDS-PAGE for Research Grade Gedivumab.


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