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Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO) (HB996046)

Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)
Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)
Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)
Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)
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Overview
Catalog No.HB996046
Description
Blinatumomab (HB996046) is a research-grade recombinant antibody targeting CD19. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesMouse
ClonalityMonoclonal
Isotype(scFv-kappa-heavy)-(scFv-heavy-kappa)
Target B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Purified by Nickel column.
Accession P15391 & P07766
Form Liquid
Storage buffer 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, CD19, AMG103, BITEMT-103, MEDI-538, MT103, bscCD19xCD3, 853426-35-4
BackgroundBlinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia.
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control BiTE Format Isotype Control for Bispecific Reference Antibody (HP473013)
Images
  • Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)

  • Anti-Human CD19 & CD3 epsilon Bispecific Reference Antibody (Blinatumomab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Blinatumomab.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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