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Research Grade Ravulizumab (HF687016)

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Spec:
  • 100ug
  • 1mg
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Overview
Catalog No.HF687016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHumanized
IsotypeIgG2-G4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetCPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionP01031
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesALXN-1210, ravulizumab-cwvz, 1803171-55-2
BackgroundRavulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis.
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Ravulizumab.

  • Bioactivity

    Detects Human C5 in indirect ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Ravulizumab.

References

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