Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO) (HF977036)

Name: Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO)
Brand: abinScience
SKU: HF977036
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HF977036
Description	Livmoniplimab (HF977036) is a research-grade recombinant antibody targeting Transforming growth factor beta-1 proprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG4-kappa
Target	LAP, Latency-associated peptide, TGF-beta-1, TGFB, TGFB1, Transforming growth factor beta-1, Transforming growth factor beta-1 proprotein, D11S833E, GARP, Garpin, Glycoprotein A repetitions predominant, LRRC32, Leucine-rich repeat-containing protein 32, Transforming growth factor beta activator LRRC32
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01137 & Q14392
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, ABBV-151, ARGX-115, MHG-8, MHGARP-8, PR-17628442412004-88-5
Background	Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

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Bioactivity

SEC-HPLC detection for Research Grade Livmoniplimab.

References

Datasheet

Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO).pdf

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Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO) (HF977036)

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References

Datasheet

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