Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO) (HY105016)

Name: Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO)
Brand: abinScience
SKU: HY105016
Price: 320 USD
Availability: InStock

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Overview

Catalog No.	HY105016
Description	Fazpilodemab (HY105016) is a research-grade recombinant antibody targeting CD331. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG1-kappa
Expression system	Mammalian cells
Target	FLT2, HBGFR, BFGFR, FGFR-1, CEK, Fibroblast growth factor receptor 1, FGFR1, bFGF-R-1, Fms-like tyrosine kinase 2, FGFBR, FLT-2, CD331, Basic fibroblast growth factor receptor 1, FLG, Proto-oncogene c-Fgr, N-sam, Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P11362 & Q86Z14
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, BFKB8488A, 2517935-02-1
Background	Fazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD).
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE for Research Grade Fazpilodemab

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Datasheet

Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO).pdf

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Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO) (HY105016)

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Datasheet

SDS

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