| Catalog No. | HY422046 |
|---|
| Species reactivity | Human |
|---|
| Applications | ELISA, Functional assay, Research in vivo |
|---|
| Isotype | Fusion - [ICOSLG N-terminal fragment (1-122)]2 - IGHG1 Fc (Fragment constant) |
|---|
| Expression system |
Mammalian Cells |
| Target |
CD28, TP44, T-cell-specific surface glycoprotein CD28, CD278, ICOS, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, AILIM |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
P10747 & Q9Y6W8 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | ALPN-101, ICOSLvIgD-Fc, 2270247-50-0 |
|---|
| Background | Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS)/CD28 antagonist. Acazicolcept has anti-inflammatory activities.
|
|---|
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
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