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Research Grade Anti-HIV gp120SU (VRC01) (VK645016)

Research Grade Anti-HIV gp120SU (VRC01)
Research Grade Anti-HIV gp120SU (VRC01)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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Overview
Catalog No.VK645016
Description
Anti-HIV gp120SU (VRC01) (VK645016) is a research-grade recombinant antibody targeting gp120SU. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman immunodeficiency virus 1
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1
Clone IDVRC01
Expression system Mammalian Cells
Clonality Monoclonal
Target gp120SU
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q75760, Q2N0S6, C6ZIG9
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background

Envelope glycoprotein gp160 (gp120SU) is a ~96 kDa protein. Envelope glycoprotein gp160: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Anti-HIV gp120SU (VRC01)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-HIV gp120SU (VRC01).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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