| Catalog No. | HB823026 |
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| Species reactivity | Human |
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| Applications | ELISA, Functional assay, Research in vivo |
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| Host species | Human |
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| Isotype | Fusion - ALB (albumin, human serum albumin, HSA) 25-609 - IFNA2 (interferon alpha 2) *b (R46, H57) 24-188 |
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| Expression system | Mammalian Cells |
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| Target | IFNAR1/IFNAR2 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Purified by ion exchange chromatography. |
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| Accession | P17181, P48551 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | Alb-IFNA2R23(608), Albumin-interferonalpha-2b, JoulferonZALBIN™ |
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| Background | Albinterferon alfa-2B (alb-IFN) is a recombinant protein consisting of interferon alfa-2b genetically fused to human albumin. Albinterferon alfa-2B can be used for the research of chronic hepatitis C.
• The Role of Structure in the Biology of Interferon Signaling., PMID:33281831
• Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation., PMID:35907379
• Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2., PMID:38802340
• IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections., PMID:30473701
• Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication., PMID:39100665
• Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling., PMID:36118237
• Structure-function of type I and III interferons., PMID:38608537
• Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury., PMID:24480543
• Mechanism of Rhinovirus Immunity and Asthma., PMID:34691038
• Structural basis for the recognition of IFNAR1 by the humanized therapeutic monoclonal antibody QX006N for the treatment of systemic lupus erythematosus., PMID:38649079
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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