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Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO) (HB912016)

Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO)
Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO)
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Overview
Catalog No.HB912016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG1-kappa
Clone IDMik beta 1
Expression system Mammalian cells
Target IL-2R subunit beta, Interleukin-15 receptor subunit beta, IL2RB, IL-2 receptor subunit beta, CD122, High affinity IL-2 receptor subunit beta, p75, Interleukin-2 receptor subunit beta, IL-2RB, p70-75, IL15RB
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P14784
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesMik-beta-1, Mikbeta1, Mik-beta1
Background

Interleukin-2 receptor subunit beta (CD122/IL2RB) is a ~61 kDa protein. Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.

1. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770
2. Zhang, Z. et al. (2019) The Journal of experimental medicine 216, 1311-1327. PMID: 31040185
References 1. J Hakimi, et al. Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC. J Immunol. 1993 Jul 15;151(2):1075-85. [HB912016]
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images
  • Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human IL-2 R beta Reference Antibody (Mik beta 1, RUO)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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