Research Grade Anti-Human CLEC2D/OCIL/LLT1 (ZM008) (HP960016)

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100ug
1mg

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Overview

Catalog No.	HP960016
Description	Anti-Human CLEC2D/OCIL/LLT1 (ZM008) (HP960016) is a research-grade recombinant antibody targeting CLAX. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	ZM008
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	CLAX, C-type lectin domain family 2 member D, Osteoclast inhibitory lectin, CLEC2D, Lectin-like transcript 1, Lectin-like NK cell receptor, OCIL, LLT-1, LLT1
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9UHP7
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	ZM008
Background	C-type lectin domain family 2 member D (CLEC2D/OCIL) is a ~21 kDa protein. Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. 1. Rosen, DB. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7796-9. PMID: 16339513 2. Germain, C. et al. (2010) The Journal of biological chemistry 285, 36207-15. PMID: 20843815 3. Hu, YS. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 89-99. PMID: 14753741 4. Gange, CT. et al. (2004) The Journal of biological chemistry 279, 29043-9. PMID: 15123656 5. Mathew, PA. et al. (2004) Molecular immunology 40, 1157-63. PMID: 15104121
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CLEC2D/OCIL/LLT1 (ZM008)
Bioactivity

Detects recombinant human CLEC2D/OCIL/LLT1 (Catalog No: HP960012) in indirect ELISA

References

Datasheet

Research Grade Anti-Human CLEC2D/OCIL/LLT1 (ZM008).pdf

Formula

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Working Solution

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Recombinant Proteins

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Research Grade Anti-Human CLEC2D/OCIL/LLT1 (ZM008) (HP960016)

Overview

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Datasheet

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