

| Catalog No. | HW675016 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Host species | Human |
| Isotype | IgG |
| Clone ID | DX-2240 |
| Expression system | Mammalian cells |
| Clonality | Monoclonal |
| Target | TIE, Tyrosine-protein kinase receptor Tie-1, TIE1 |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P35590 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | DX-2240, DX2240, DX2240 |
| Background | Tyrosine-protein kinase receptor Tie-1 (TIE1) is a ~125 kDa protein. Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. |
| References | 1. Dransfield D, et al. Targeting Tie-1 inhibits tumor growth and sensitizes the tumor vasculature to anti-angiogenics[J]. Cancer Research, 2008, 68(9_Supplement): 1520-1520. [HW675016] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human TIE1 (DX-2240)



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