

| Catalog No. | HY036116 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, Functional assay, Research in vivo |
| Host species | Human |
| Clonality | Monoclonal |
| Isotype | Fusion - Homo sapiens IDS (iduronate 2-sulfatase, ID2S) Pr26-550 (1:1) - IGHG4 Fc (Fragment constant) |
| Target | CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR, Alpha-L-iduronate sulfate sulfatase, EC:3.1.6.13, IDS, Iduronate 2-sulfatase, Iduronate 2-sulfatase 14 kDa chain, Iduronate 2-sulfatase 42 kDa chain, Idursulfase, SIDS |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P02786 & P22304 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 2641020-57-5, DNL310, DNL-310 |
| Background | Iduronate 2-sulfatase (IDS/Idursulfase) is a ~61 kDa protein. Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. |
| References | 1. Arguello A, et al. Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome. JCI Insight. 2021 Oct 8;6(19):e145445. [HY036116] 2. Freeman C, et al. Lysosomal degradation of heparin and heparan sulphate. Adv Exp Med Biol. 1992;313:121-34. [HY036116] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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