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Research Grade Anti-Human IL21 Antibody (NN9828) (HV658036)

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Research Grade Anti-Human IL21 Antibody (NN9828)

Research Grade Anti-Human IL21 Antibody (NN9828)

Research Grade Anti-Human IL21 Antibody (NN9828)

Research Grade Anti-Human IL21 Antibody (NN9828)

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Spec:

100ug
1mg

Number:

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Overview
Images
References
Datasheet

Overview

Catalog No.	HV658036
Description	Anti-Human IL21 Antibody (NN9828) (HV658036) is a research-grade recombinant antibody targeting IL-21. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Clone ID	NN9828
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	IL-21, Interleukin-21, IL21, Za11
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9HBE4
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background	Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

Detects Human IL21 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL21 Antibody (NN9828).

References

Datasheet

Research Grade Anti-Human IL21 Antibody (NN9828).pdf

Formula

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Research Grade Anti-Human IL21 Antibody (NN9828)