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Anti-Human CXCR1/IL-8RA&CXCR2/IL-8RB Reference Antibody (Eltrekibart, RUO) (HY553016)

Anti-Human CXCR1/IL-8RA&CXCR2/IL-8RB Reference Antibody (Eltrekibart, RUO)
Anti-Human CXCR1/IL-8RA&CXCR2/IL-8RB Reference Antibody (Eltrekibart, RUO)
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Overview
Catalog No.HY553016
Description
Eltrekibart (HY553016) is a research-grade recombinant antibody targeting CXCL1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target CXCL1, GROA, GRO1, Neutrophil-activating protein 3, GRO, C-X-C motif chemokine 1, NAP-3, Growth-regulated alpha protein, MGSA, SCYB1, Melanoma growth stimulatory activity, GRO-alpha(1-73), GROB, CXCL2, Growth-regulated protein beta, Macrophage inflammatory protein 2-alpha, SCYB2, HSF, Gro-beta, Hematopoietic synergistic factor, MIP2-alpha, C-X-C motif chemokine 2, MIP2A, GRO2, SB-251353, GRO-beta-T, GRO3, CXCL3, GRO-gamma, Macrophage inflammatory protein 2-beta, GRO-gamma(1-73), C-X-C motif chemokine 3, GROG, Growth-regulated protein gamma, MIP2-beta, SCYB3, C-X-C motif chemokine 5, ENA-78(1-78), Neutrophil-activating peptide ENA-78, ENA78, SCYB5, Small-inducible cytokine B5, CXCL5, Epithelial-derived neutrophil-activating protein 78, C-X-C motif chemokine 6, SCYB6, Small-inducible cytokine B6, CXCL6, CKA-3, Chemokine alpha 3, Granulocyte chemotactic protein 2, GCP2, GCP-2, NAP-2, NAP-2(1-63), NAP-2(73), PPBP, CXCL7, PBP, Small-inducible cytokine B7, Macrophage-derived growth factor, LA-PF4, Leukocyte-derived growth factor, CTAP-III, CTAP-III(1-81), Low-affinity platelet factor IV, TGB1, Beta-TG, C-X-C motif chemokine 7, MDGF, Platelet basic protein, LDGF, NAP-2(74), THBGB1, NAP-2(1-66), CTAP3, SCYB7, GCP/IL-8 protein II, MDNCF, IL8/NAP1 form III, IL-8(1-77), Neutrophil-activating factor, GCP/IL-8 protein I, GCP/IL-8 protein VI, Interleukin-8, Chemokine (C-X-C motif) ligand 8, Neutrophil-activating protein 1, Monocyte-derived neutrophil chemotactic factor, (Ser-IL-8)72, MDNCF-b, LYNAP, GCP/IL-8 protein V, IL8/NAP1 form IV, MONAP, IL8/NAP1 form V, IL8/NAP1 form VI, NAP-1, Granulocyte chemotactic protein 1, GCP/IL-8 protein III, IL8/NAP1 form II, IL8, IL-8, CXCL8, IL8/NAP1 form I, (Ala-IL-8)77, Protein 3-10C, GCP/IL-8 protein IV, Emoctakin, GCP-1, C-X-C motif chemokine 8, NAF, T-cell chemotactic factor, MDNCF-c, Monocyte-derived neutrophil-activating peptide, Lymphocyte-derived neutrophil-activating factor
Endotoxin level Please contact the lab for this information.
Purity >95% purity by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P09341, P19875, P19876, P42830, P80162, P02775, P10145
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2484883-56-7
Background

Growth-regulated alpha protein (CXCL1/2) is a ~11 kDa protein. Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human CXCR1/IL-8RA&CXCR2/IL-8RB Reference Antibody (Eltrekibart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Eltrekibart.

References
Formula
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