Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 Bispecific Reference Antibody (Enristomig, RUO) (HC336156)

Name: Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 Bispecific Reference Antibody (Enristomig, RUO)
Brand: abinScience
SKU: HC336156
Price: 176 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC336156

Description

Enristomig (HC336156) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Species reactivity

Human

Applications

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

Host species

Human

Clonality

Monoclonal

Isotype

Ig VH-VH'-G1(h-CH2-CH3)

Tested applications

Target

4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9, B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1

Endotoxin level

< 10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q07011 & Q9NZQ7

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Bispecific, Tetravalent, 2539845-73-1

Background

Enristomig is an anti-TNFRSF9/CD274 monoclonal antibody.

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Enristomig.
Bioactivity

Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Bioactivity

Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD137 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD137 (Catalog No: HC336011)
Lane 2: recombinant human CD3E (Catalog No: HV974011)
Immunofluorescence

Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.
Immunofluorescence

Immunofluorescence staining of HEK293T cells overexpressing PD-L1 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.