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Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65534, RUO) (VK646036)

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Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65534, RUO)
Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65534, RUO)
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Overview
Catalog No.VK646036
Description
Anti-Orthohantavirus puumalaense GP Antibody (ADI-65534) (VK646036) is a research-grade recombinant antibody targeting Envelopment polyprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityOrthohantavirus puumalaense (Puumala virus) (PUUV), Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV), Seoul virus (SEOV), Dobrava-Belgrade orthohantavirus (Dobrava virus) (DOBV), Andes virus (Andes orthohantavirus), Sin Nombre orthohantavirus (SNV)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1
Clone IDADI-65534
Expression system Mammalian cells
Clonality Monoclonal
Target Envelopment polyprotein, M polyprotein
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P41264
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelope glycoprotein (GP/Envelopment polyprotein) is a ~29 kDa protein. Forms homotetramers with glycoprotein N at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.

Note For research use only. Not suitable for clinical or therapeutic use.
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  • Anti-Hantavirus Glycoprotein GP Broadly Neutralizing Reference Antibody (ADI-65534, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Orthohantavirus puumalaense GP Antibody (ADI-65534)

References
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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