Research Grade Etakafusp Alfa (HF815016)

Name: Research Grade Etakafusp Alfa
Brand: abinScience
SKU: HF815016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HF815016
Description	Etakafusp Alfa (HF815016) is a research-grade recombinant antibody targeting CD8. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	Humanized immunoglobulin G1-kappa anti-(human CD8) fused at the C-terminus of one heavy chain, via peptide linker to a variant of human IL2
Target	CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8B, CD8B1, CD8b, T-cell surface glycoprotein CD8 beta chain
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01732, P10966
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2852680-28-3
Background	T-cell surface glycoprotein CD8 alpha chain (CD8 & IL2) is a ~25 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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Research Grade Etakafusp Alfa.pdf

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Research Grade Etakafusp Alfa (HF815016)

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