| Catalog No. | HF001016 |
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| Species reactivity | Human |
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| Applications | ELISA, Functional assay, Research in vivo |
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| Isotype | Glucagon-like peptide 2 (GLP-2) analogue, fused to an Fc Fragment of Human IgG4 |
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| Expression system | Mammalian Cells |
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| Target | GLP-2R, Glucagon-like peptide 2 receptor, GLP-2 receptor, GLP2R, GLP-2-R |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | O95838 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | 2854391-99-2 |
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| Background | HY-P990967 is an GLP1R-targeting human antibody.
• A cross-platform approach identifies genetic regulators of human metabolism and health., PMID:33414548
• Expression, purification and molecular dynamics simulation of extracellular domain of glucagon-like peptide-2 receptor linked to teduglutide., PMID:34174312
• Human Epicardial Fat Expresses Glucagon-Like Peptide 1 and 2 Receptors Genes., PMID:28514806
• Epicardial, pericardial fat and glucagon-like peptide-1 and -2 receptors expression in stable patients with multivessel coronary artery disease: an association with the renin-angiotensin-aldosterone system., PMID:33544567
• New Avenues in the Regulation of Gallbladder Motility-Implications for the Use of Glucagon-Like Peptide-Derived Drugs., PMID:30137354
• Methylation Status of GLP2R, LEP and IRS2 in Small for Gestational Age Children with and without Catch-up Growth., PMID:32936762
• The safety of available treatment options for short bowel syndrome and unmet needs., PMID:34105428
• Novel agonist and antagonist radioligands for the GLP-2 receptor. Useful tools for studies of basic GLP-2 receptor pharmacology., PMID:34855984
• Increased GLP2R expression in gastric chief cells of patients with severe obesity regardless of diabetes status., PMID:28337026
• GLP-2 receptors in human disease: high expression in gastrointestinal stromal tumors and Crohn's disease., PMID:22951144
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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