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Research Grade Sphingomab (YP926026)

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  • 100ug
  • 1mg
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Overview
Catalog No.YP926026
Species reactivityGeneral
ApplicationsResearch Grade Biosimilar
Host speciesMouse
IsotypeIgG2a (Need Ca2+)
Expression systemMammalian Cells
TargetS1P, Sphingosine-1-phosphate
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesLT1002
BackgroundSphingomab is a monoclonal antibody that specifically targets S1P (Sphingosine-1-phosphate), a bioactive lipid with diverse signaling functions. S1P promotes endothelial cell migration and survival, contributing to blood vessel formation and stabilization.S1P regulates immune cell trafficking and influences inflammatory responses.S1P is overexpressed in various tumors (e.g., breast cancer, melanoma), promoting tumor growth, angiogenesis, and metastasis.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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