Research Grade Efaxaglutide Alfa (HW328076)

Name: Research Grade Efaxaglutide Alfa
Brand: abinScience
SKU: HW328076
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HW328076
Description	Research Grade Efaxaglutide Alfa (HW328076) is a monoclonal antibody detecting GLP-1R.
Species reactivity	Human
Applications	ELISA, FCM, Functional assay
Clonality	Monoclonal
Isotype	GLP1-exendin 4-Fc
Expression system	Mammalian cells
Nature	Recombinant
Target	GCG, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP-2, GRPP, Glicentin, Glicentin-related polypeptide, Glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, Incretin hormone, OXM, OXY, Oxyntomodulin, Pro-glucagon, Exenatide, Exendin-4
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01275 & P26349
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Alternate Names	CAS: 3069923-11-8
Background	Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. 1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722 2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095 3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125 4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449 5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895 6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285 7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712
Note	For research use only. Not suitable for clinical or therapeutic use.

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Datasheet

Research Grade Efaxaglutide Alfa.pdf

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Formula

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Research Grade Efaxaglutide Alfa (HW328076)

Overview

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Datasheet

SDS