Anti-HRSV Fusion Protein Reference Antibody (Palivizumab, RUO) (VK421406)

Name: Anti-HRSV Fusion Protein Reference Antibody (Palivizumab, RUO)
Brand: abinScience
SKU: VK421406
Price: 370 USD
Availability: InStock

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Spec:

100ug
1mg

Number:

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK421406

Description

Anti-HRSV Fusion Protein Reference Antibody (Palivizumab, RUO) (VK421406) is a human monoclonal antibody detecting F/Fusion glycoprotein F0.

Species reactivity

Human respiratory syncytial virus A (HRSV-A), Human respiratory syncytial virus B (HRSV-B)

Applications

ELISA, FCM, Functional assay

Host species

Human

Clonality

Monoclonal

Isotype

IgG1(LALA-PG), kappa

Expression system

Mammalian cells

Nature

Recombinant

Target

F, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03420

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..

Background

Fusion glycoprotein F0 is a ~56 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

References

Datasheet

Anti-HRSV Fusion Protein Reference Antibody (Palivizumab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HRSV Fusion Protein Reference Antibody (Palivizumab, RUO) (VK421406)

Overview

Images

References

Datasheet

SDS