Human FOXN1 Recombinant Protein (N-His) (HC891012)

Name: Human FOXN1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC891012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC891012
Description	Recombinant Human FOXN1 Protein, N-His (HC891012) expressed in E. coli, spanning Ile273-Arg389. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O15353
Protein length	Ile273-Arg389
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	15.81 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	FOXN1, Forkhead box protein N1, RONU, WHN, Winged-helix transcription factor nude
Background	Forkhead box protein N1 is a ~68 kDa protein. Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. 1. Vigliano, I. et al. (2011) Journal of medical genetics 48, 413-6. PMID: 21507891
Note	For research use only

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Datasheet

Human FOXN1 Recombinant Protein (N-His).pdf

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Human FOXN1 Recombinant Protein (N-His) (HC891012)

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