

| Catalog No. | HC962012 |
|---|---|
| Description |
Recombinant Human SERF1A Protein, N-His-KSI (HC962012) expressed in E. coli, spanning Ala2-Ile110. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O75920 |
| Protein length | Ala2-Ile110 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 27.98 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | FAM2A, Protein 4F5, SERF1, SERF1A, SMA modifier 1, SMAM1, Small EDRK-rich factor 1, h4F5 |
| Background | Small EDRK-rich factor 1 is a ~12 kDa protein. Positive regulator of amyloid protein aggregation and proteotoxicity. Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates. 1. van Ham, TJ. et al. (2010) Cell 142, 601-12. PMID: 20723760 2. Falsone, SF. et al. (2012) Cell reports 2, 358-71. PMID: 22854022 3. Merle, DA. et al. (2019) Journal of molecular biology 431, 2581-2598. PMID: 31034892 |
| Note | For research use only |
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