

| Catalog No. | HD116012 |
|---|---|
| Description |
Recombinant Human RPS15A Protein, N-His (HD116012) expressed in E. coli, spanning Met1-Phe130. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P62244 |
| Protein length | Met1-Phe130 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 17.00 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 40S ribosomal protein S15a, RPS15A, Small ribosomal subunit protein uS8 |
| Background | Small ribosomal subunit protein uS8 is a ~14 kDa protein. Component of the small ribosomal subunit. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Required for proper erythropoiesis. 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797 3. Ikeda, F. et al. (2017) Haematologica 102, e93-e96. PMID: 27909223 |
| Note | For research use only |
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