

| Catalog No. | HD377012 |
|---|---|
| Description |
Recombinant Human GATA6 Protein, N-His (HD377012) expressed in E. coli, spanning Gly375-Gln489. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q92908 |
| Protein length | Gly375-Gln489 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 14.97 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | GATA-binding factor 6, GATA6, Transcription factor GATA-6 |
| Background | Transcription factor GATA-6 is a ~60 kDa protein. Transcriptional activator. Regulates SEMA3C and PLXNA2. Involved in gene regulation specifically in the gastric epithelium. May regulate genes that protect epithelial cells from bacterial infection. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. 1. Kodo, K. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 13933-8. PMID: 19666519 2. Yang, YQ. et al. (2012) European journal of medical genetics 55, 520-6. PMID: 22750565 3. Li, J. et al. (2012) International journal of molecular medicine 30, 783-90. PMID: 22824924 4. Tucker, NR. et al. (2017) Heart rhythm 14, 284-291. PMID: 27756709 5. Yoshida, T. et al. (1997) FEBS letters 414, 333-7. PMID: 9315713 6. Shapira, M. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 14086-91. PMID: 16968778 7. Oulès, B. et al. (2020) Nature communications 11, 5067. PMID: 33082341 |
| Note | For research use only |
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