Canine IFN-gamma Recombinant Protein (C-His) (CF813011)

Name: Canine IFN-gamma Recombinant Protein (C-His)
Brand: abinScience
SKU: CF813011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	CF813011
Description	Recombinant Dog IFNG/IFN-gamma Protein, C-His (CF813011) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE.. Highlights ●High Purity — >90% as determined by SDS-PAGE.
Expression system	Mammalian cells
Accession	P42161
Protein length	Gln24-Lys166
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Canis lupus familiaris (Dog) (Canis familiaris)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.77 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IFN-gamma, IFNG, Interferon gamma
Background	Interferon gamma is a ~19 kDa protein. Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.
Note	For research use only

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Datasheet

Canine IFN-gamma Recombinant Protein (C-His).pdf

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Canine IFN-gamma Recombinant Protein (C-His) (CF813011)

Overview

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Datasheet

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