Human BLOC1S1 Recombinant Protein (N-His) (HD961012)

Name: Human BLOC1S1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD961012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD961012
Description	Recombinant Human BLOC1S1 Protein, N-His (HD961012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P78537
Protein length	Gln24-Ser153
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BLOC-1 subunit 1, BLOC1S1, BLOS1, Biogenesis of lysosome-related organelles complex 1 subunit 1, EC:2.3.1.-, GCN5-like protein 1, GCN5L1, Protein RT14, Protein acetyltransferase BLOC1S1, RT14
Background	Biogenesis of lysosome-related organelles complex 1 subunit 1 is a ~17 kDa protein. Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. 1. Setty, SR. et al. (2007) Molecular biology of the cell 18, 768-80. PMID: 17182842 2. Pu, J. et al. (2015) Developmental cell 33, 176-88. PMID: 25898167
Note	For research use only

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Datasheet

Human BLOC1S1 Recombinant Protein (N-His).pdf

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Human BLOC1S1 Recombinant Protein (N-His) (HD961012)

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