Recombinant Mouse CD40LG Protein, N-His (MB199022)

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Overview

Catalog No.	MB199022
Description	Recombinant Mouse CD40LG Protein, N-His (MB199022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P27548
Protein length	Met112-Leu260
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD154, CD40 ligand, CD40 ligand, membrane form, CD40 ligand, soluble form, CD40-L, Cd40l, Cd40lg, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tnfsf5, Tumor necrosis factor ligand superfamily member 5, sCD40L
Background	CD40 ligand is a ~29 kDa protein. Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. 1. Armitage, RJ. et al. (1992) Nature 357, 80-2. PMID: 1374165
Note	For research use only

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Datasheet

Recombinant Mouse CD40LG Protein, N-His.pdf

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Recombinant Mouse CD40LG Protein, N-His (MB199022)

Overview

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