

| Catalog No. | MB243012 |
|---|---|
| Description |
Recombinant Mouse CXCR2 Protein, N-His-KSI (MB243012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | P35343 |
| Protein length | Gly2-Ser47&Ala105-Lys119&Arg183-Arg207&Asp273-Lys293 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | C-X-C chemokine receptor type 2, CD182, CXC-R2, CXCR-2, Cmkar2, Cxcr2, GRO/MGSA receptor, Gpcr16, High affinity interleukin-8 receptor B, IL-8R B, Il8rb |
| Background | C-X-C chemokine receptor type 2 is a ~40 kDa protein. Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. 1. McDonald, B. et al. (2010) Science (New York, N.Y.) 330, 362-6. PMID: 20947763 |
| Note | For research use only |
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