Mouse GOLGA2 Recombinant Protein (N-His) (MC396012)

Name: Mouse GOLGA2 Recombinant Protein (N-His)
Brand: abinScience
SKU: MC396012
Price: 211 USD
Availability: InStock

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Catalog No.	MC396012
Description	Recombinant Mouse GOLGA2 Protein, N-His (MC396012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q921M4
Protein length	Ser459-Ser729
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	130 kDa cis-Golgi matrix protein, GM130, Golga2, Golgin subfamily A member 2
Background	Golgin subfamily A member 2 is a ~113 kDa protein. Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgi disassembly: phosphorylation at Ser-37 by CDK1 at the onset of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPI vesicles and thereby inhibiting transport through the Golgi apparatus during mitosis. Also plays a key role in spindle pole assembly and centrosome organization. 1. Liu, C. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 346-351. PMID: 28028212 2. Zhang, CH. et al. (2011) Cell cycle (Georgetown, Tex.) 10, 1861-70. PMID: 21552007
Note	For research use only

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Mouse GOLGA2 Recombinant Protein (N-His).pdf

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Mouse GOLGA2 Recombinant Protein (N-His) (MC396012)

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