Mouse AIFM1 Recombinant Protein (N-His) (MF658012)

Name: Mouse AIFM1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MF658012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MF658012
Description	Recombinant Mouse AIFM1 Protein, N-His (MF658012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9Z0X1
Protein length	Val131-Lys321
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Aif, Aifm1, Apoptosis-inducing factor 1, mitochondrial, EC:1.6.99.-, Pdcd8, Programmed cell death protein 8
Background	Apoptosis-inducing factor 1, mitochondrial is a ~66 kDa protein. Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. Release into the cytoplasm is mediated upon binding to poly-ADP-ribose chains. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. 1. Yu, SW. et al. (2002) Science (New York, N.Y.) 297, 259-63. PMID: 12114629 2. Wang, Y. et al. (2011) Science signaling 4, ra20. PMID: 21467298 3. Susin, SA. et al. (1999) Nature 397, 441-6. PMID: 9989411 4. Sevrioukova, IF. (2009) Journal of molecular biology 390, 924-38. PMID: 19447115
Note	For research use only

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Datasheet

Mouse AIFM1 Recombinant Protein (N-His).pdf

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Mouse AIFM1 Recombinant Protein (N-His) (MF658012)

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