Mouse MYOC Recombinant Protein (N-His) (MV725012)

Name: Mouse MYOC Recombinant Protein (N-His)
Brand: abinScience
SKU: MV725012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MV725012
Description	Recombinant Mouse MYOC Protein, N-His (MV725012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	O70624
Protein length	Cys231-Met490
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Myoc, Myocilin, Myocilin 20 kDa N-terminal fragment, Myocilin 35 kDa N-terminal fragment, Myocilin, C-terminal fragment, Myocilin, N-terminal fragment, Tigr, Trabecular meshwork-induced glucocorticoid response protein
Background	Myocilin is a ~55 kDa protein. Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. 1. Kwon, HS. et al. (2013) The Journal of biological chemistry 288, 16882-16894. PMID: 23629661 2. Kwon, HS. et al. (2013) The Journal of biological chemistry 288, 26357-71. PMID: 23897819 3. Joe, MK. et al. (2012) The Journal of biological chemistry 287, 13216-27. PMID: 22371502
Note	For research use only

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Datasheet

Mouse MYOC Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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Mouse MYOC Recombinant Protein (N-His) (MV725012)

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