Mouse IL-15 Recombinant Protein (N-His) (MW541022)

Name: Mouse IL-15 Recombinant Protein (N-His)
Brand: abinScience
SKU: MW541022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MW541022
Description	Recombinant Mouse IL15 Protein, N-His (MW541022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P48346
Protein length	Asn49-Ser162
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IL-15, Il15, Interleukin-15
Background	Interleukin-15 is a ~18 kDa protein. Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems. Stimulates the proliferation and activation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines. In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection. Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits. Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5. 1. Mattei, F. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 1179-87. PMID: 11466332 2. Khan, IA. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 2103-8. PMID: 8757333 3. Masuda, A. et al. (2000) The Journal of biological chemistry 275, 29331-7. PMID: 10882748 4. Mirghomizadeh, F. et al. (2009) Experimental cell research 315, 3064-75. PMID: 19632221
Note	For research use only

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Mouse IL-15 Recombinant Protein (N-His).pdf

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Mouse IL-15 Recombinant Protein (N-His) (MW541022)

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