Mouse E2F1 Recombinant Protein (N-His) (MX082012)

Name: Mouse E2F1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MX082012
Price: 211 USD
Availability: InStock

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Catalog No.	MX082012
Description	Recombinant Mouse E2F1 Protein, N-His (MX082012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q61501
Protein length	Leu169-Glu295
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	E2F-1, E2f1, Transcription factor E2F1
Background	Transcription factor E2F1 is a ~46 kDa protein. Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. 1. Porse, BT. et al. (2001) Cell 107, 247-58. PMID: 11672531 2. Zaragoza, K. et al. (2010) Molecular and cellular biology 30, 2293-304. PMID: 20176812 3. Holmberg, C. et al. (1998) Oncogene 17, 143-55. PMID: 9674698
Note	For research use only

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Datasheet

Mouse E2F1 Recombinant Protein (N-His).pdf

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Mouse E2F1 Recombinant Protein (N-His) (MX082012)

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