Mouse NR3C1 Recombinant Protein (N-His) (MY450012)

Name: Mouse NR3C1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MY450012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MY450012
Description	Recombinant Mouse NR3C1 Protein, N-His (MY450012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P06537
Protein length	Ala571-Lys792
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	GR, Glucocorticoid receptor, Grl, Grl1, Nr3c1, Nuclear receptor subfamily 3 group C member 1
Background	Glucocorticoid receptor is a ~87 kDa protein. Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. 1. McNally, JG. et al. (2000) Science (New York, N.Y.) 287, 1262-5. PMID: 10678832 2. Tronche, F. et al. (2004) Genes & development 18, 492-7. PMID: 15037546
Note	For research use only

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Datasheet

Mouse NR3C1 Recombinant Protein (N-His).pdf

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Mouse NR3C1 Recombinant Protein (N-His) (MY450012)

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