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M. pneumoniae Adhesin P40 Recombinant Protein (N-His) (JN180042)

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Overview
Catalog No.JN180042
Description
Recombinant M. pneumoniae Adhesin P40 Protein, N-His (JN180042) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
Expression systemE. coli
AccessionQ50341
Protein lengthAsn26-Ala290
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesMycoplasma pneumoniae
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesAdhesin P40, Adhesin P40/P90, Adhesin P90, Protein B, Protein C, orf6
Background

Adhesin P40/P90 is a ~130 kDa protein. Part of major adhesin Nap complex of the attachment organelle which mediates attachment to host ciliated epithelium and plays a major role in gliding motility. Binds sialylated oligosaccharides, which are present on the surface of its human host cells and which probably serve as the main host cell receptors for this bacterium. This protein and P1 mutually stabilize each other, and are required for formation of the attachment organelle.

1. Sperker, B. et al. (1991) Molecular microbiology 5, 299-306. PMID: 1904124
2. Vizarraga, D. et al. (2020) Nature communications 11, 5188. PMID: 33057023
3. Vizarraga, D. et al. (2025) PLoS pathogens 21, e1012973. PMID: 40153444
4. Marseglia, A. et al. (2024) International journal of biological macromolecules 279, 135277. PMID: 39226978
Note For research use only
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Formula
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Formula
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