

| Catalog No. | VK169011 |
|---|---|
| Description |
SEOV Glycoprotein Gn Recombinant Protein (C-His) (VK169011) expressed in Mammalian cells. Purity: >90% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| Expression system | Mammalian cells |
| Accession | P28729 |
| Protein length | Leu17-Ala484 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Seoul virus (SEOV) |
| Nature | Recombinant |
| Endotoxin level | <0.1 EU/ug as determined by LAL method. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 54.44 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | Envelopment polyprotein, GP, Glycoprotein G1, Glycoprotein N, Gn |
| Background | Envelopment polyprotein (Mgp1/membrane glycoprotein polyprotein) is a ~116 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after clathrin-mediated endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins during virus assembly. 1. Hofmann, H. et al. (2013) Journal of virology 87, 4384-94. PMID: 23388721 |
| Note | For research use only |




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